The PWA Blood Bank was established in 1982 in response to a desperate need felt to begin a crusade against professional blood donors who were mostly drug addicts and carriers of  various transmittable diseases.

Today PWA Blood Bank is considered to be one of the largest and  reputed blood banks in the country registered under the Sindh Transfusion of Safe Blood Act, 1997.

With a daily output of 3 bags in 1982, to a current output of over 200 bags, PWA Blood Bank is catering to the requests from all over the city and provides on exchange basis, healthy, screened and cross matched blood and its components to the patients, totally free of cost. Each blood bag dispatched, goes through a stringent process of screening for HIV I and II, Hepatitis B, Hepatitis C, Syphilis and Malaria.

Besides whole blood, PWA Blood Bank is also providing different components of blood including packed cells, fresh frozen plasma and manual units of platelets.

From 2008 PWA has started the facility of providing mega unit of platelets(concentrated form of platelets) only for civil which is required for the patients suffering from dengue, aplastic anemia and those undergoing chemotherapy.
A single process of Mega Unit costs around Rs. 10,000 but at PWA, the facility is provided absolutely free of cost.

PWA Blood Bank stands unique among different Blood Banks in that it provides blood on exchange basis without involving a single rupee for screening and cross matching and all expenses are borne from zakat and donations.